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DB has brought to the fore once again the challenging debate between those who argue that all research involving embryonic stem cells is immoral and those who see immense medical potential in this area of research. As a clinical geneticist raised in the Christian tradition and interested in gene hunting and cancer chemoprevention I can claim to offer a dispassionate opinion. Three aspects of stem cell research in which my Newcastle colleagues have special interest are mitochondrial transplantation, in vitro gamete development, and human admixed embryos. In all cases, legitimate clinical targets may be presented as a powerful argument in favour of avoiding blanket legal barriers. Counter-arguments combine anxiety about misuse of funds, threats to the structure of the family, and the dangers of cross species transfer of pathogens and unexpected malformation.
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